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Table 3 Correlation between cerebrospinal fluid FL-Ng, CT-Ng, SNAP-25, synaptotagmin, 215–223, and synaptotagmin, 238–245 levels for the clinical studya

From: Full-length and C-terminal neurogranin in Alzheimer’s disease cerebrospinal fluid analyzed by novel ultrasensitive immunoassays

  FL-Ng FL-Ng FL-Ng
Control (N = 26) MCI-AD (N = 18) AD (N = 23)
CT-Ng rho = 0.815, P < 0.00001 rho = 0.279, N.S. rho = 0.595, P = 0.003
SNAP-25 rho = 0.601, P = 0.001 rho = 0.329, N.S. rho = 0.306, N.S.
Synaptotagmin, 215–223 rho = 0.642, P = 0.0004 rho = 0.340, N.S. rho = 0.577, P = 0.004
Synaptotagmin, 238–245 rho = 0.640, P = 0.0004 rho = 0.344, N.S. rho = 0.585, P = 0.003
  CT-Ng CT-Ng CT-Ng
Control (N = 26) MCI-AD (N = 18) AD (N = 23)
FL-Ng rho = 0.815, P < 0.00001 rho = 0.279, N.S. rho = 0.595, P = 0.003
SNAP-25 rho = 0.736, P = 0.00002 rho = 0.458, N.S. rho = 0.636, P = 0.001
Synaptotagmin, 215–223 rho = 0.815, P < 0.00001 rho = 0.512, P = 0.04 rho = 0.677, P = 0.0004
Synaptotagmin, 238–245 rho = 0.805, P < 0.00001 rho = 527, P = 0.03 rho = 0.702, P = 0.0002
  1. aCorrelations presented by Spearman’s rank correlation coefficient (rho). Non-significant (N.S.) correlation coefficients (P > 0.05)
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Alzheimer's Research & Therapy

ISSN: 1758-9193