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Table 2 Correlation between cerebrospinal fluid FL-Ng, CT-Ng, age, MMSE, and biomarker levels for the clinical studya

From: Full-length and C-terminal neurogranin in Alzheimer’s disease cerebrospinal fluid analyzed by novel ultrasensitive immunoassays

  FL-Ng FL-Ng FL-Ng
Control (N = 26) MCI-AD (N = 18) AD (N = 23)
Age rho = − 0.136, N.S. rho = 0.430, N.S. rho = 0.061, N.S.
MMSE rho = − 0.001, N.S. rho = 0.172, N.S. rho = − 0.241, N.S.
Aβ1–42 rho = 0.655, P = 0.0003 rho = 0.351, N.S. rho = −0.017, N.S.
T-tau rho = 0.739, P = 0.00002 rho = 0.268, N.S. rho = 0.500, P = 0.015
P-tau rho = 0.627, P = 0.001 rho = 0.257, N.S. rho = 0.391, N.S.
  CT-Ng CT-Ng CT-Ng
Control (N = 26) MCI-AD (N = 18) AD (N = 23)
Age rho = −0.044, N.S. rho = 0.010, N.S. rho = 0.043, N.S.
MMSE rho = 0.077, N.S. rho = 0.245, N.S. rho = −0.132, N.S.
Aβ1–42 rho = 0.782, P = 0.0003 rho = 0.194, N.S. rho = 0.032, N.S.
T-tau rho = 0.787, P < 0.00001 rho = 0.326, N.S. rho = 0.664, P = 0.0006
P-tau rho = 0.677, P = 0.0002 rho = 0.621, P = 0.008 rho = 0.728, P = 0.00008
  1. aCorrelations presented by Spearman’s rank correlation coefficient (rho). Non-significant (N.S.) correlation coefficients (P > 0.05)
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Alzheimer's Research & Therapy

ISSN: 1758-9193