Skip to main content
Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: The molecular tweezer CLR01 improves behavioral deficits and reduces tau pathology in P301S-tau transgenic mice

Fig. 2

CLR01 protects P301S-tau mice from deterioration of muscle strength. P301S-tau and wild-type littermate mice were tested using the grip-strength assay on days 1, 17/18, and 35 of the treatment. a Treatment effect in all vehicle-treated P301S-tau mice. b Treatment effect in female, vehicle-treated, P301S-tau mice. c Treatment effect in male, vehicle-treated, P301S-tau mice. d Comparison of all treatment groups. e Comparison of the treatment groups, separated by sex, at the end of the experiment. The color key in panel E is for both panels d and e. The data in these two panels are presented as mean ± SD. P values were calculated using a one-way ANOVA (panels ac), two-way, repeated-measure ANOVA (panel d), and two-way ANOVA (panel e) with post hoc Tukey test in all cases

Back to article page