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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease

Fig. 3

Inter-group metabolite differences stratified by gender. Boxplots highlighting differences between metabolite concentrations in serum when comparing Alzheimer’s disease (AD), mild cognitive impairment (MCI) and age-matched controls (CTL). Boxplots were fitted with a linear model coloured by gender (red = female, blue = male). Boxplots are shown for the metabolites in the serotonin and kynurenine pathways that reported significant differences between participant groups (Supplementary Figs. S1 and S2). The plots suggest that the observed lower concentrations in metabolites between groups CTL > MCI > AD follow a similar trend across both genders

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