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Table 2 Gray matter volume reductions in amnestic mild cognitive impairment, compared to age-matched normal controls

From: Differences between memory encoding and retrieval failure in mild cognitive impairment: results from quantitative electroencephalography and magnetic resonance volumetry

  x, y, z coordinate Label Cluster level Peak level
p (FWE-corr) equivk p (FWE-corr) T equivZ
Amnestic MCI 21 − 21 12 Thalamus Lt < 0.001 2324 < 0.001 7.84 7.34
− 12 − 41 6 Precuneus Lt    < 0.001 5.75 5.54
− 30 − 21 − 23 Parahippocampus Lt    0.001 5.62 5.42
53 0 − 11 Temporal Sup Rt < 0.001 1573 < 0.001 5.70 5.49
60 − 21 − 14 Temporal Mid Rt    0.001 5.48 5.30
51 − 9 − 23 Temporal Mid Rt    0.002 5.37 5.19
12 20 32 Cingulum Mid Rt < 0.001 567 < 0.001 5.68 5.47
12 30 33 Cingulum Mid Rt    0.003 5.23 5.07
14 33 24 Cingulum Mid Rt    0.006 5.09 4.94
− 29 21 42 Frontal Mid Lt   371 < 0.001 5.66 5.46
− 29 33 33 Frontal Sup Lt    0.001 5.45 5.26
− 36 21 33 Frontal Mid Lt    0.009 4.99 4.85
36 33 24 Frontal Mid Rt   241 0.001 5.63 5.4
29 27 38 Frontal Mid Rt    0.003 5.23 5.06
− 45 9 − 24 Temporal Pole Sup Lt   433 0.001 5.53 5.34
− 27 − 3 48 Precentral Lt   166 0.001 5.47 5.28
12 51 32 Frontal Sup Medial Rt   328 0.001 5.41 5.23
18 41 35 Frontal Sup Rt    0.002 5.38 5.20
23 51 23 Frontal Sup Rt    0.003 5.24 5.07
33 − 23 − 20 Parahippocampus Rt   621 0.002 5.32 5.15
30 − 5 − 30 Parahippocampus Rt    0.004 5.19 5.03
27 − 32 − 3 Hippocampus Rt   225 0.004 5.15 5.00
Encoding failure − 20 − 20 14 Thalamus Lt < 0.001 2926 < 0.001 6.7 6.25
− 12 − 38 6 Hippocampus Lt    < 0.001 6.59 6.15
− 26 − 23 − 9 Hippocampus Lt    < 0.001 6.34 5.95
26 − 33 − 3 Hippocampus Rt < 0.001 879 < 0.001 6.32 5.93
29 − 26 − 8 Hippocampus Rt    < 0.001 6.12 5.76
32 − 23 − 17 Hippocampus Rt    < 0.001 5.79 5.49
30 − 5 − 30 Parahippocampus Rt 0.002 160 < 0.001 6.02 5.68
Retrieval failure − 21 − 23 9 Thalamus Lt 0.001 201 0 6.61 6.14
17 11 59 Frontal Sup Rt 0.002 174 0 5.86 5.53
51 0 − 11 Temporal Sup Rt < 0.001 390 0.002 5.53 5.24
44 − 17 − 9 Temporal Sup Rt    0.003 5.41 5.14
44 − 3 − 18 Temporal Sup Rt    0.018 4.92 4.71
11 26 36 Cingulum Mid Rt 0.004 111 0.005 5.25 5
  1. FWE, p < 0.05. Local maximum more than 8.0 mm apart. MCI mild cognitive impairment, FWE family-wise error, Rt right, Lt left, Sup superior, Mid middle