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Table 3 Study-based age- and gender-standardized prevalence estimates for subjective cognitive decline (SCD; last column) and cumulative frequency estimates for the stepwise application of SCD operationalization criteria according to qualitative harmonization

From: Estimating prevalence of subjective cognitive decline in and across international cohort studies of aging: a COSMIC study

Study SCD operationalization criteria
Criterion 1
Endorsement of a self-experienced decline in cognitive capacity without objective cognitive impairment
+ Criterion 2
Intact functional ability
+ Criterion 3
No major depression
+ Criterion 4
No anxiety disorder
% (95%CI)
ActiveAging 27.98 (21.44–34.52) 25.81 (19.41–32.20) 25.73 (19.36–32.10) N/A
CFAS 17.04 (15.45–18.64) 15.59 (14.00–17.18) 12.73 (11.41–14.05) 6.34 (5.57–7.20)
EAS 15.84 (12.57–19.10) 13.82 (10.90–16.73) 15.23 (10.95–19.51) 12.05 (5.80–18.30)
EPIDEMCA 50.52 (48.36–52.69) 47.74 (45.51–49.98) 25.83 (23.80–27.86) 23.86 (21.93–25.79)
ESPRIT 18.17 (16.52–19.82) 16.60 (15.02–18.18) 13.36 (11.92–14.80) 10.35 (9.11–11.60)
Invece.Ab 14.60 (11.63–17.56) 14.02 (10.89–17.16) 12.31 (9.43–15.18) 10.76 (8.28–13.23)
KLOSCAD 63.65 (62.28–65.02) 58.02 (57.88–59.46) 42.25 (40.82–43.68) 42.27 (40.90–43.66)
LEILA75+ 12.88 (11.65–14.12) 11.70 (10.48–12.92) 9.80 (8.64–10.96) N/A
LRGS-TUA 51.23 (48.15–54.31) 47.39 (44.32–50.47) 46.84 (43.80–49.87) N/A
MAAS 65.26 (60.33–70.20) 60.52 (55.35–65.69) 54.97 (49.43–60.50) 52.70 (47.43–57.96)
MoVIES 32.82 (30.35–35.32) 30.45 (28.01–32.90) 27.27 (24.89–29.65) N/A
PATH 8.95 (7.89–10.01) 8.23 (7.21–9.26) 7.34 (6.36–8.33) 6.06 (5.13–6.99)
SGS 18.47 (16.82–20.13) 16.52 (14.93–18.10) 10.24 (8.94–11.55) 9.91 (8.64 (11.18)
SLASII 12.16 (10.53–13.79) 10.82 (9.27–12.36) 10.28 (8.78–11.78) 9.89 (8.50–11.28)
SydneyMAS 42.77 (40.49–45.04) 39.10 (36.70–41.51) 32.58 (30.14–35.01) 26.98 (24.55–29.40)
ZARADEMP 44.68 (42.98–46.38) 42.04 (40.31–43.77) 29.42 (27.77–31.06) 28.12 (26.50–29.74)
Total* 33.03 (32.56–33.49) 30.46 (30.01–30.92) 24.08 (23.65–24.51) 23.83 (23.29–24.36)
  1. 95%CI 95% confidence interval, N/A not available
  2. *Unstandardized