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Table 4 Adjusted odds ratio in 5-year cognitive change across ATP-III lipid categories at baseline, OR (95%CI)

From: Sex-specific associations between lipids and cognitive decline in the middle-aged and elderly: a cohort study of Chinese adults

  Global cognition Mental status Episodic memory
Male Female   Male Female   Male Female
Total cholesterol (mg/dl)
 < 200 ref ref ref ref ref ref
 200~239 1.011 (0.848, 1.206) 1.010 (0.833, 1.226) 1.179 (0.983, 1.414) 1.175 (0.972, 1.421) 1.035 (0.869, 1.233) 0.914 (0.752, 1.111)
 240+ 1.051 (0.807, 1.369) 1.242 (0.965, 1.600) 0.889 (0.681, 1.162) 1.295 (1.002, 1.675) b 1.040 (0.780, 1.387) 1.014 (0.791, 1.300)
LDL-c (mg/dl)
 < 100 ref ref ref Ref ref ref
 100~129 0.979 (0.813, 1.178) 1.308 (1.051, 1.627) b 0.996 (0.827, 1.199) 1.302 (1.047, 1.618) b 1.004 (0.835, 1.207) 1.207 (0.973, 1.496)
 130~159 0.918 (0.727, 1.160) 1.291 (1.017, 1.639) b 0.984 (0.776, 1.248) 1.357 (1.071, 1.720) a 0.943 (0.748, 1.189) 1.058 (0.828, 1.351)
 160~189 0.976 (0.696, 1.367) 1.377 (1.002, 1.891) b 0.873 (0.611, 1.249) 1.491 (1.076, 2.066) b 1.134 (0.790, 1.629) 1.120 (0.819, 1.531)
 190+ 0.998 (0.644, 1.546) 1.424 (0.933, 2.172) 0.807 (0.505, 1.289) 1.283 (0.838, 1.967) 1.283 (0.802, 2.054) 0.903 (0.576, 1.415)
HDL-c (mg/dl)
 < 40 ref ref ref ref ref ref
 40~59 0.822 (0.679, 0.994) a 1.159 (0.928, 1.447) 0.808 (0.665, 0.980) b 1.161 (0.933, 1.443) 0.861 (0.711, 1.042) 1.087 (0.873, 1.354)
 60+ 0.794 (0.629, 1.001) 1.294 (1.002, 1.671) b 0.769 (0.614, 0.964) b 1.246 (0.967, 1.606) 0.898 (0.711, 1.134) 1.245 (0.966, 1.605)
Triglycerides (mg/dl)
 < 150 ref ref ref ref ref ref
 150~199 0.981 (0.766, 1.257) 1.015 (0.795, 1.296) 1.008 (0.781, 1.302) 1.184 (0.938, 1.494) 0.870 (0.675, 1.120) 0.800 (0.630, 1.015)
 200+ 1.088 (0.863, 1.371) 0.836 (0.663, 1.054) 1.097 (0.864, 1.394) 0.955 (0.760, 1.200) 1.043 (0.819, 1.329) 0.804 (0.628, 1.031)
  1. OR odds ratio, CI confidence interval, LDL-c low-density lipoprotein cholesterol, HDL-c high-density lipoprotein cholesterol
  2. Adjusted for baseline age, education, marital status, registered residence, body mass index, alcohol use, smoking status, diabetes, hypertension, social activity, health insurance status, and lipid-lowering medication use
  3. aP < 0.05 after the Bonferroni correction
  4. bP < 0.05 before the Bonferroni correction