Table 2 Associations of baseline glomerular filtration rate (GFR_crcys) estimated by the CKD-EPI equations with incidence of dementia and Alzheimer’s disease

  GFR_crcys > 80 ml/min/1.73 m²

Ref

Ref

Ref

Ref

  67 ≤ GFR_crcys < 80 ml/min/1.73 m²

2.77 (1.53 to 5.05)

0.001

1.87 (1.02 to 3.44)

0.04

3.60 (1.77 to 7.32)

< 0.001

2.27 (1.10 to 4.68)

0.03

  GFR_crcys < 67 ml/min/1.73 m²

4.90 (2.79 to 8.63)

< 0.001

2.19 (1.21 to 3.95)

0.009

5.06 (2.54 to 10.10)

< 0.001

2.14 (1.04 to 4.40)

0.04

  GFR_crcys > 80 ml/min/1.73 m²

Ref

Ref

Ref

Ref

  67 ≤ GFR_crcys < 80 ml/min/1.73 m²

2.71 (1.38 to 5.33)

0.004

1.78 (0.89 to 3.55)

0.10

3.99 (1.72 to 9.26)

0.001

2.47 (1.05 to 5.86)

0.04

  GFR_crcys < 67 ml/min/1.73 m²

4.59 (2.42 to 8.71)

< 0.001

2.19 (1.12 to 4.29)

0.02

6.03 (2.67 to 13.64)

< 0.001

2.80 (1.19 to 6.58)

0.02