Number (%)
|
199
|
161 (81)
|
38 (19)
|
161
|
137 (85)
|
24 (15)
|
38
|
24 (63)
|
14 (37)
|
Mean age (SD), years
|
70 (6)
|
69 (6)
|
72 (5)b
|
69 (6)
|
69 (6)
|
71 (5)
|
71 (7)
|
69 (6)
|
74 (6)
|
Female, n (%)
|
89 (45)
|
72 (45)
|
17 (45)
|
73 (45)
|
61 (45)
|
12 (50)
|
16 (42)
|
11 (46)
|
5 (36)
|
Mean education (SD), years
|
14 (3)
|
14 (3)
|
14 (4)
|
14 (3)
|
14 (3)
|
14 (4)
|
14 (4)
|
14 (4)
|
14 (3)
|
APOE-ε4 carriers/homozygous, n (%)
|
92/7 (46)
|
70/5 (43)
|
22/2 (58)
|
82/6 (51)
|
65/5 (47)
|
17/1 (71)a
|
10/1 (26)
|
5/0 (21)
|
5/1 (36)
|
Median MMSE (IQR), /30
|
29 (2)
|
29 (2)
|
29 (2)a
|
29 (2)
|
29 (2)
|
29 (2)
|
29 (2)
|
29 (1)
|
27 (3)a
|
Median ELISA plasma Aβ1–42/Aβ1–40 (IQR)
|
0.17 (0.03)
|
0.18 (0.03)
|
0.15 (0.02)d
|
0.18 (0.03)
|
0.18 (0.03)
|
0.15 (0.02)d
|
0.17 (0.02)
|
0.18 (0.03)
|
0.16 (0.01)b
|
Median ELISA plasma Aβ1–42/t-tau (IQR)
|
1.23 (0.50)
|
1.32 (0.49)
|
1.00 (0.29)d
|
1.25 (0.49)
|
1.29 (0.49)
|
1.02 (0.34)c
|
1.21 (0.58)
|
1.41 (0.51)
|
0.89 (0.27)d
|
Median SIMOA plasma Aβ1–42/Aβ1–40 (IQR)
|
0.26 (0.06)
|
0.26 (0.06)
|
0.21 (0.05)d
|
0.26 (0.06)
|
0.26 (0.05)
|
0.21 (0.05)d
|
0.24 (0.07)
|
0.28 (0.06)
|
0.22 (0.03)c
|
Median SIMOA plasma Aβ1–42/t-tau (IQR)
|
0.93 (0.41)
|
0.99 (0.39)
|
0.73 (0.24)d
|
0.94 (0.37)
|
0.99 (0.38)
|
0.74 (0.27)c
|
0.92 (0.45)
|
1.14 (0.33)
|
0.70 (0.21)d
|