Alpha-amylase 1A copy number variants and the association with memory performance and Alzheimer’s dementia

Table 4 Associations between Montreal Cognitive Assessment test scores and AMY1A copy number variation

	MoCA test participants (n = 791) Mean ± SD
AMY1 copy number	Total MoCA score	Word recall score
By four groups
1–5	25.5 (3.0)	3.0 (1.3)
6 (reference)¹	25.1 (3.3)	2.8 (1.4)
7–9	25.5 (3.1)^a	3.1 (1.4)
≥ 10	25.7 (3.1)	3.2 (1.2)*

Data is presented as mean (SD)
Data is analyzed using one-way ANOVA with Tukey post hoc test *p value < 0.05
¹The most common AMY1A copy number variant is 6 and is therefore used as the reference group
^aMissing data (n = 1)

ISSN: 1758-9193