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Table 1 Clinical and demographic characteristics of the included Alzheimer’s Disease Neuroimaging Initiative (ADNI) participants

From: Amyloid biomarkers as predictors of conversion from mild cognitive impairment to Alzheimer’s dementia: a comparison of methods

  Training dataset (n = 159) Test dataset (n = 129)
MCI-c (n = 41) MCI-nc (n = 118) MCI-c (n = 29) MCI-nc (n = 101)
Mean age (± S.D.) [years] 72 ± 7 73 ± 8 73 ± 7 73 ± 8
Sex [m/f] 14/27 55/63 15/14 59/42
Mean Aβ42/Aβ40 in CSF (± S.D.) Not assessed 0.10 ± 0.06 0.15 ± 0.06
PES of ADCRP (± S.D.) 18 ± 19 − 6 ± 18 16 ± 13 − 2 ± 17
Median follow-up time (95% C.I.) [months] 48 (36–51) 47 (35–51)
Cox-SUVR (± S.D.) 1.7 ± 0.3 1.4 ± 0.2 1.6 ± 0.2 1.5 ± 0.2
Composite SUVR (± S.D.) Not assessed 1.6 ± 0.2 1.4 ± 0.2
  1. MCI-c mild cognitive impairment–converters, MCI-nc MCI non-converters, S.D. standard deviation, CSF cerebrospinal fluid, PES pattern expression score, SUVR standardized uptake value ratio