Table 1 Descriptive data
|  | All, n = 151 | AD, n = 64 | AD high NPS, n = 34, cohort 1 | AD low NPS, n = 30, cohort 2 | SCI, n = 30, cohort 2 | MCI, N = 12, cohort 1 | MIX, N = 27, cohort 1 | VaD, N = 18, cohort 1 |
|---|---|---|---|---|---|---|---|---|
Females (n) | 92 (61%) | 39 (61%) | 20 (59%) | 19 (63%) | 13 (43%) | 10 (83%) | 19 (70%) | 11 (61%) |
Age, years | 76.0 (18.0) | 78.0 (16)A | 79.5 (8.0)A,B | 70.0 (19.0) | 60.0 (7.0) | 82.0 (6.5)A,B | 83.0 (6.0)A,B | 75.5 (9.0)A |
MMSE (0–30 points) | 22.0 (7.0) | 20.0 (4.5)A, C | 19.5 (6.0)A,C | 21.0 (2.0)A | 30.0 (1.0) | 25.5 (2.5) | 20.0 (5.0)A | 22.0 (6.0)A |
CDR (0–3 points) | 1.4 (0.6) | m.d | 1.5 (1) | m.d | m.d | 1 (0.5) | 1.5 (1) | 1.4 (1) |
Ng pg/ml | 246 (150) | 279 (142)A | 249 (148) | 295 (86.0) | 175 (85) | 314 (223) | 244 (177) | 218 (119) |
GAP-43 pg/ml | 3643 (2211) | 4065 (2077)A | 3901 (2190) | 4229 (1818) | 2357 (964) | 3955 (2586)A | 3639 (2750)A | 3698 (741)A |
NFL ng/ml | 1530 (1370) | 1670 (1360)A | 1970 (1540) | 1455 (710) | 620 (420) | 1770 (1500)A | 2150 (1620)A | 1780 (1800)A |
Aβ1–42 pg/ml | 460 (280) | 410 (33) | 440 (170) | 396 (84) | 805 (200) | 490 (250) | 435 (160) | 460 (220) |
T-tau pg/ml | 630 (430) | 698 (391) | 680 (400) | 719 (470) | 265 (92) | 730 (430) | 695 (220) | 550 (330) |
P-tau pg/ml | 85 (56) | 98 (37) | 87 (52) | 104 (31) | 45 (18) | 99 (48) | 97 (39) | 74 (33) |
Cornell (0–38 points) | 4.0 (5.0) | 4.0 (4.5) | 5.0 (5.0) | 2.0 (5.0) | 4.0 (4.0) | 5.5 (5.0) | 5.0 (4.0) | 6.0 (4.0) |
NPI (0–144 points) | 47 (39) | m.d | 42 (29) | m.d | m.d | 56 (48) | 47 (52) | 45.5 (26) |