Fig. 1From: α-Secretase nonsense mutation (ADAM10 Tyr167*) in familial Alzheimer’s diseaseFamily tree including ADAM10 Tyr167*mutation and clinical status. CT scan images of the three affected siblings showing patterns of atrophy. Black M+, affected carrier; white WT, non-affected wild-type; gray, possibly affected. Age at onset (AO), at death (AD), or current age (CA) in years. Chromatogram of the mutation is also shownBack to article page