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Table 3 Partial least square regression models

From: Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study

Index

NFL VIPsa

t-TAU VIPsa

Sex

0.01

1.83

Age

2.74

0.18

t-TAU

1.53

 

NFL

 

0.82

Amyloid PET SUVR

0.69

0.08

APOE ɛ4

0.14

0.53

Cognitive score

 MMSE

1.47

0.72

 FCSRT

0.94

0.62

Clinical characteristics

 AF

0.77

0.29

 BMI

1.25

0.81

 Diabetes

0.38

0.56

 Dyslipidemia

0.06

0.34

 Head trauma

0.20

0.53

 HTA

1.27

0.22

 IHD

1.21

0.47

 Mood Disorders

0.01

1.19

 OSAS

0.80

1.04

 Plasma Vit. B12 deficiency

0.01

2.48

  1. AF atrial fibrillation, BMI body mass index, FCSRT free and cued selective reminding test, HTA arterial hypertension, IHD ischemic heart disease, MMSE Mini-Mental State Examination, NFL neurofilament light chain, OSAS obstructive sleep apnea syndrome, SD standard deviation, SMC subjective memory complaints, SUVR standardized uptake value ratio, t-Tau total Tau, VIPs variable importance for the projection
  2. aVIPs is considered significant when ≥ 1.5