Skip to main content

Table 3 Regression coefficients and odds ratios (95% confidence intervals) from binary logistic regression to predict the presence of ≥ 1 NPS on the NPI-Q

From: Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers—results from the DELCODE study

 

Whole sample (n = 296)

Cognitively healthy (CO + SCD + REL) (n = 190)

Cognitively healthy worrier (n = 100)

Cognitively healthy non-worrier (n = 88)

Predictors

OR (95% CI), p value

OR (95% CI), p value

OR (95% CI), p value

OR (95% CI), p value

Age

1.002 (0.958–1.048), 0.921

1.028 (0.971–1.089), 0.343

1.019 (0.943–1.102), 0.631

1.015 (0.914–1.127), 0.787

Sex

0.972 (0.583–1.621), 0.913

1.108 (0.560–2.191), 0.769

1.099 (0.434–2.782), 0.843

1.235 (0.397–3.847), 0.716

Education

0.968 (0.888–1.056), 0.467

1.018 (0.911–1.137), 0.757

1.070 (0.924–1.238), 0.365

0.904 (0.729–1.121), 0.357

MEM

0.597 (0.414–0.862), 0.006**

0.486 (0.226–1.048), 0.066

0.662 (0.258–1.698), 0.391

0.293 (0.069–1.244), 0.096

AĂź42 (pg/ml)

0.999 (0.998–1.000), 0.030*

1.000 (0.998–1.001), 0.353

0.999 (0.998–1.000), 0.124

1.001 (0.999–1.003), 0.180

t-tau (pg/ml)

0.999 (0.996–1.001), 0.243

0.999 (0.995–1.003), 0.571

0.999 (0.994–1.004), 0.780

1.000 (0.993–1.000), 0.960

p-tau (pg/ml)

1.013 (0.993–1.034), 0.211

1.011 (0.981–1.042), 0.482

1.017 (0.977–1.058), 0.409

0.987 (0.928–1.050), 0.688

  1. Note: * p < .05, ** p < .01. Aβ42 beta-amyloid 42, CO healthy controls, CI confidence interval, MEM memory factor score, OR odds ratio, p-tau phospho-tau, REL first-degree relatives of AD patients, SCD subjective cognitive decline, t-tau total tau