Table 1 Demographic characteristics of the study participants

n

96

105

71

Age (years)

66.3 ± 9.5

71.1 ± 9.1^a

74.4 ± 9.3^a

Sex (M to F)

36: 60

41: 64

17: 54

Education (years)

11.9 ± 4.5

11.2 ± 4.5

9.8 ± 5.7^a

Duration (years)

n.a.

2.3 ± 1.3

3.5 ± 1.5^b

ApoE ε4 genotype

17/96 (18%)

30/105 (29%)

30/71 (42%)^a

Amyloid positivity

9/96 (9%)

49/105 (47%)^a

56/71 (79%)^ab

MMSE

28.2 ± 1.8

25.7 ± 2.7^a

19.1 ± 5.3^ab

CDR-SB

0

1.5 ± 1.0^a

5.0 ± 2.5^ab

Total cognition score

183.2 ± 33.8

135.2 ± 33.6^a

86.4 ± 34.7^ab

 Memory

73.3 ± 20.6

44.1 ± 17.9^a

23.6 ± 13.9^ab

 Language

23.8 ± 3.1

20.5 ± 4.2^a

16.2 ± 5.6^ab

 Visuospatial

33.1 ± 4.7

29.6 ± 7.2^a

21.0 ± 11.5^ab

 Frontal/executive

42.1 ± 9.2

31.5 ± 10.3^a

17.8 ± 9.3^ab

 Attention

10.9 ± 2.5

9.6 ± 2.7^a

8.1 ± 2.6^ab