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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Combination of plasma amyloid beta(1-42/1-40) and glial fibrillary acidic protein strongly associates with cerebral amyloid pathology

Fig. 3

ROCs for amyloid PET positivity in the total study population (a) and non-demented subset (b). Individual plasma biomarkers GFAP, Abeta(1-42/1-40), and NfL are plotted as well as the combined panel best predicting amyloid PET positivity. Panel in the total population (a) are the predicted values of the combined plasma Abeta(1-42/1-40), plasma GFAP, age, and APOE ε4 carriership panel (AUC = 0.88 (95% CI 0.83–0.93)). Panel in the non-demented population (SCD + MCI) (b) are the predicted values of the combined plasma Abeta(1-42/1-40), plasma GFAP, and APOE ε4 carriership panel (AUC = 0.84 (95% CI 0.76–0.92)). GFAP, glial fibrillary acidic protein; Abeta, amyloid beta; NfL, neurofilament light

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Alzheimer's Research & Therapy

ISSN: 1758-9193