N | Controls | Early presymptomatic | Late presymptomatic | Symptomatic |
---|
39 | 10 | 11 | 17 |
---|
Age, years (mean (SD)) | 44.6 (9.5) | 34.8 (5.5)* | 41.9 (8.4) | 47.6 (9.0) |
Gender, m/f | 15/24 | 3/7 | 5/6 | 10/7 |
EYO, years (mean (SD)) | – | − 11.8 (2.6) | − 3.3 (4.6) | 4.8 (4.0)^ |
Global CDR (mean (SD)) | 0 | 0 | 0 | 0.85 (0.39)** |
- For comparison of age, unadjusted linear regression was used; for comparison of CDR, Fisher’s exact test was used
- EYO estimated years to onset, CDR Clinical Dementia Rating scale
- *Evidence of a difference (p < 0.05) compared with controls
- **Evidence of a difference (p < 0.001) compared with controls
- ^2 missing values