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Table 1 Participant demographics

From: Measuring cortical mean diffusivity to assess early microstructural cortical change in presymptomatic familial Alzheimer’s disease

N

Controls

Early presymptomatic

Late presymptomatic

Symptomatic

39

10

11

17

Age, years (mean (SD))

44.6 (9.5)

34.8 (5.5)*

41.9 (8.4)

47.6 (9.0)

Gender, m/f

15/24

3/7

5/6

10/7

EYO, years (mean (SD))

− 11.8 (2.6)

− 3.3 (4.6)

4.8 (4.0)^

Global CDR (mean (SD))

0

0

0

0.85 (0.39)**

  1. For comparison of age, unadjusted linear regression was used; for comparison of CDR, Fisher’s exact test was used
  2. EYO estimated years to onset, CDR Clinical Dementia Rating scale
  3. *Evidence of a difference (p < 0.05) compared with controls
  4. **Evidence of a difference (p < 0.001) compared with controls
  5. ^2 missing values