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Table 1 Participant demographics

From: Measuring cortical mean diffusivity to assess early microstructural cortical change in presymptomatic familial Alzheimer’s disease

N Controls Early presymptomatic Late presymptomatic Symptomatic
39 10 11 17
Age, years (mean (SD)) 44.6 (9.5) 34.8 (5.5)* 41.9 (8.4) 47.6 (9.0)
Gender, m/f 15/24 3/7 5/6 10/7
EYO, years (mean (SD)) − 11.8 (2.6) − 3.3 (4.6) 4.8 (4.0)^
Global CDR (mean (SD)) 0 0 0 0.85 (0.39)**
  1. For comparison of age, unadjusted linear regression was used; for comparison of CDR, Fisher’s exact test was used
  2. EYO estimated years to onset, CDR Clinical Dementia Rating scale
  3. *Evidence of a difference (p < 0.05) compared with controls
  4. **Evidence of a difference (p < 0.001) compared with controls
  5. ^2 missing values