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Table 4 Eye and systemic disease and NfL levels

From: Neurofilament light chain in the vitreous humor of the eye

Predictor Beta SE t p value
Macular degeneration − 1.06 1.38 − 0.77 0.44
Diabetic retinopathy (DR) 0.45 0.61 0.74 0.46
Age-related cataract (ARC) 1.21 1.01 1.19 0.24
ARC + DR 0.22 0.61 0.36 0.72
Cataract surgery − 0.32 0.68 − 0.47 0.64
Glaucoma − 0.61 0.90 − 0.68 0.50
Epiretinal membrane − 1.20 0.74 − 1.62 0.11
Retinal detachment − 0.29 0.67 − 0.43 0.67
Macular hole − 0.15 0.84 − 0.17 0.86
Proliferative diabetic retinopathy (stage 4 DR vs. no DR) 0.45 0.62 0.73 0.47
Hypertension 0.28 0.70 0.40 0.69
Diabetes 0.62 0.61 1.01 0.31
Hyperlipidemia − 0.034 0.63 − 0.05 0.96
  1. No significant association was found between vitreous NfL and the various ophthalmic and systemic diseases in this patient population (p > 0.05)