Table 1 Patient demographics and overall sample breakdown
From: Neurofilament light chain in the vitreous humor of the eye
Characteristic | Overall sample breakdown (N = 77) |
Sex | |
 Male | 49 (63.63%) |
 Female | 28 (36.36%) |
Age | |
 Mean age ± SD | 56.21 ± 15.52 |
 Age > 40 | 68 (88.31%) |
 Age > 50 | 53 (68.83%) |
 Age > 60 | 35 (45.45%) |
Race | |
 Asian | 3 (3.90%) |
 American Indian or Alaskan Native | 2 (2.60%) |
 Black or African | 27 (35.06%) |
 Hispanic | 11 (14.29%) |
 White | 26 (33.77%) |
 Others | 8 (10.39%) |
Ethnicity | |
 Hispanic | 20 (25.97%) |
 Not Hispanic | 57 (74.03%) |
Education level | |
 8th grade or less | 11 (14.29%) |
 High school | 28 (36.36%) |
 College or greater | 38 (49.35%) |
Eye disease category | |
 Age-related macular degeneration | 4 (5.19%) |
 Diabetic retinopathy | 35 (45.45%) |
 Age-related cataracts | 66 (85.71%) |
 Glaucoma | 10 (12.99%) |
 Epiretinal membrane | 17 (22.08%) |
 Retinal detachment | 32 (41.56%) |
 Macular hole | 12 (15.58%) |
 APOE allele | Overall sample breakdown (n = 76, 152 alleles) |
 ε2 (may offer some protection against AD) | 15 (9.87%) |
 ε3 (neutral risk for AD) | 121 (79.61%) |
 ε4 (increases risk for AD at an earlier age) | 16 (10.52%) |
APOE genotype | Overall sample breakdown (n = 77) |
 ε22 | 0 (0.0%) |
 ε23 | 11 (14.29%) |
 ε24 | 4 (5.19%) |
 ε33 | 45 (58.44%) |
 ε34 | 16 (20.78%) |
 ε44 | 0 (0.0%) |
MMSE scores, mean ± SD | Mean ± SD (n = 77) |
 No cognitive impairment (n = 68) | 27.91 ± 1.68 |
 Mild or severe cognitive impairment (n = 9) | 19.44 ± 2.35 |