Fig. 4
From: Amyloid-β1–43 cerebrospinal fluid levels and the interpretation of APP, PSEN1 and PSEN2 mutations
CSF levels of sAPPα, sAPPβ, Aβ1–43/sAPPα and Aβ1–43/sAPPβ ratios in the three mutation carrier groups compared to controls. Scatter plots show sAPPα (a), sAPPβ (b), Aβ1–43/sAPPα (c) and Aβ1–43/sAPPβ (d) CSF levels in controls and in carriers of known pathogenic mutations, of VUS and of PSEN1 p.E318G. Values of mean ± SD are given. p value indicators correspond to the values assessed with Kruskal-Wallis: *p < 0.05, ***p < 0.0001