Fig. 2
From: Association of carotid and intracranial stenosis with Alzheimer’s disease biomarkers
Representative MR angiographic images of intracranial and neck vessels, and coronal sections of T1-weighted images showing medial temporal structures including the bilateral hippocampi of CI individuals in the a stenosis− group and b stenosis+ group with regard to number of stenotic intracranial arteries ≥ 2. a Stenosis−: MR angiography of a 77-year-old woman with MCI with no steno-occlusive lesions in both intracranial and neck vessels. HVa was − 1052 mm3, and no significant hippocampal atrophy was observed in coronal sections on T1-weighted MRI. b Stenosis+: MR angiography of an 81-year-old woman with MCI with multifocal intracranial arterial stenosis, while no steno-occlusive lesions were found in the extracranial carotid arteries. HVa was − 3862 mm3, and coronal sections on T1-weighted MRI indicate bilateral hippocampal atrophy. MR, magnetic resonance; HVa, hippocampal volume adjusted for intracranial volume; MCI, mild cognitive impairment