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Table 1 Participant demographics

From: T2 heterogeneity: a novel marker of microstructural integrity associated with cognitive decline in people with mild cognitive impairment

 

Group

HC

MCI

AD

Total

N (male to female)

97 (46:51)

49 (27:22)

10 (2:8)

156 (75:81)

Age (years)

69.3 ± 8.58

72.2 ± 9.03

77.9 ± 9.94

70.7 ± 9.05

YOE

15.8 ± 3.16

14.2 ± 2.81

13.1 ± 2.60

15.1 ± 3.13

Cognitive score (normalised to HC)

0.00 ± 1.00

− 4.08 ± 2.09

− 8.50 ± 3.15

− 1.83 ± 3.02

  1. Data show mean ± standard deviation, combined for studies 1 and 2. Cognitive score is calculated as a Z score relative to the healthy control group of each study, separately, as different cognitive tests were used (study 1: MoCA; study 2: ACE-III). For this reason, the HC group by definition has a mean ± SD of 0 ± 1. HC healthy control, MCI mild cognitive impairment, AD Alzheimer’s disease, YOE years of education