|
Non-carriers (n = 48)
|
Cognitively intact carriers (n = 35)
|
---|
LAS-FNAME
|
M (SD)
|
M (SD)
|
df
|
F
|
p valuea
|
d
|
---|
Immediate Memory
|
Face Recognition
|
11.71 (.79)
|
11.60 (.74)
|
1, 83
|
.40
|
.530
|
.14
|
Letter Recall
|
4.88 (2.60)
|
4.20 (2.29)
|
1, 83
|
1.50
|
.225
|
.28
|
Name Recognition
|
9.83 (1.70)
|
8.54 (2.45)
|
1, 83
|
8.09
|
.006*
|
.62
|
Delayed Memory
|
Face Recognition
|
11.81 (.53)
|
11.80 (2.45)
|
1, 83
|
.10
|
.919
|
.01
|
Letter Recall
|
6.06 (2.98)
|
4.80 (2.42)
|
1, 83
|
4.24
|
.043*
|
.47
|
Name Recognition
|
9.27 (2.39)
|
8.46 (2.62)
|
1, 83
|
2.17
|
.145
|
.32
|
Scale Scores
|
IM Total
|
26.42 (4.19)
|
24.34 (4.66)
|
1, 83
|
4.51
|
.037*
|
.47
|
DM Total
|
27.14 (4.88)
|
25.06 (4.93)
|
1, 83
|
3.67
|
.059
|
.42
|
LAS-FNAME Total
|
53.56 (8.76)
|
49.40 (9.26)
|
1, 83
|
4.35
|
.040*
|
.46
|
- Abbreviations: M mean, SD standard deviation, IM Immediate Memory, DM Delayed Memory, LAS-FNAME Total IM Total + DM Total, df degrees of freedom, F F-ratio, d Cohen’s d effect size
- ap value calculated for ANOVA tests for cognitively intact PSEN1 mutation carriers versus non-carriers
- *p < 0.05