TY - JOUR AU - Wei, Wei AU - Wang, Yifan AU - Liu, Yinghua AU - Dai, Chun-Ling AU - Tung, Yunn-Chyn AU - Liu, Fei AU - Iqbal, Khalid PY - 2020 DA - 2020/08/27 TI - Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice JO - Alzheimer's Research & Therapy SP - 102 VL - 12 IS - 1 AB - Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of middle-aged to old individuals. The pathophysiological process of AD is believed to begin many years before the emergence of clinical symptoms. The important influence of congenital genetic aberrations on the development of AD provides a novel opportunity to initiate prenatal to early postnatal pharmacological treatment to address the role of this critical period of brain development in the disease. SN - 1758-9193 UR - https://doi.org/10.1186/s13195-020-00666-7 DO - 10.1186/s13195-020-00666-7 ID - Wei2020 ER -