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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Normalization of CSF pTau measurement by Aβ40 improves its performance as a biomarker of Alzheimer’s disease

Fig. 2

Associations between CSF pTau and pTau/Aβ40, Aβ PET, tau PET, neurodegeneration and cognition. Associations of baseline CSF pTau and pTau/Aβ40 with baseline Aβ PET (a, b), baseline Temporal-metaROI FTP SUVR (c, d), baseline (e, f), and slope (g, h) of adjusted hippocampal volume (aHCV) (mm3), baseline (i, j) and slope (k, l) of PACC cognitive score. Different colors reflect the concordance and discordance between CSF pTau and CSF pTau/Aβ40. For example, pTau−/pTau/Aβ40− indicates the individual was negative according to both CSF pTau and CSF pTau/Aβ40, while pTau+/pTau/Aβ40− indicates the individual was positive according to CSF pTau but negative according to CSF pTau/Aβ40

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