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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Intracranial alternating current stimulation facilitates neurogenesis in a mouse model of Alzheimer’s disease

Fig. 4

iACS increased the neural proliferation in the hippocampus of 5xFAD mouse brain. A–C Cells positive for proliferation marker Ki67 were reduced in the hippocampus of 5xFAD mouse brains. iACS increased Ki67-positive cells. Scale bar 100 μm (A–C) and 20 μm (A’–C’). D The numbers of cells positive for Ki67 were significantly reduced in the hippocampus of 5xFAD mouse brain and were significantly recovered following iACS. *P < 0.05 and **P < 0.01. n = 5 mice for each group

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Alzheimer's Research & Therapy

ISSN: 1758-9193