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Table 3 Spearman correlation coefficients between CSF NRG1 and other characteristics in AD patients

From: CSF levels of the BACE1 substrate NRG1 correlate with cognition in Alzheimer’s disease

  Spearman correlation coefficients (p value)
CSF neuregulin Age MMSE CSF Aβ1–42 CSF Aβ1–40 CSF tau CSF P-tau CSF BACE1
CSF neuregulin 1        
Age − 0.14 (0.33) 1       
MMSE − 0.44 (0.001) 0.17 (0.24) 1      
CSF Aβ1–42 0.28 (0.03) 0.01 (0.92) − 0.24 (0.09) 1     
CSF Aβ1–40 − 0.07 (0.61) 0.13 (0.37) 0.15 (0.32) 0.34 (0.01) 1    
CSF tau 0.06 (0.66) − 0.10 (0.47) − 0.11 (0.45) 0.0 (0.98) 0.29 (0.04) 1   
CSF P-tau − 0.03 (0.81) − 0.04 (0.78) − 0.03 (0.83) 0.1 (0.85) 0.32 (0.02) 0.85 (< 0.001) 1  
CSF BACE1 − 0.14 (0.32) 0.08 (0.55) 0.17 (0.23) 0.05 (0.72) 0.67 (< 0.001) 0.41 (0.002) 0.39 (0.004) 1
  1. Correlations between CSF NRG1 levels and other characteristics in AD patients
  2. Spearman correlation coefficient was used for statistical analysis