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Table 2 Relationship between CSF NRG1 and groups of patients, compared to controls. Linear regression analysis models

From: CSF levels of the BACE1 substrate NRG1 correlate with cognition in Alzheimer’s disease

Groups CSF NRG1 (log)
Unadjusted Model 1a Model 2b
β (SE) p value β (SE) p value β (SE) p value
Controls Ref. Ref. Ref.
AD 0.30 (0.09) 0.001 0.31 (0.09) 0.001 0.34 (0.11) 0.003
MCI-AD 0.21 (0.11) 0.06 0.22 (0.11) 0.05 0.34 (0.12) 0.004
AD + MCI-AD 0.27 (0.08) 0.001 0.29 (0.09) 0.001 0.34 (0.10) 0.001
Other MCI 0.13 (0.10) 0.18 0.21 (0.10) 0.04 0.24 (0.10) 0.02
Other dementias 0.07 (0.10) 0.46 0.13 (0.11) 0.23 0.11 (0.11) 0.33
  1. aAdjusted on age and sex
  2. bModel 1 + MMSE score + CSF Aβ1–42