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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Longitudinal changes in EEG power, sleep cycles and behaviour in a tau model of neurodegeneration

Fig. 5

Sleep continuity changes over time in rTg4510 mice. Average sleep (NREM plus REM) bout length (> 30 s duration) during sleep from 1-week recording periods every 4 weeks in the dark (a) and light (b). Average sleep bout number from 1-week recording periods every 4 weeks in the dark (c) and light (d). Average length of REM sleep bout length (> 20 s duration) from 1-week recording periods every 4 weeks in the dark (e) and light (f). Average length of REM sleep bout number from 1-week recording periods every 4 weeks in the light (g) and dark (h). Asterisks (*) denote statistical significance (p < 0.05) at the time point between WT vs Tg, WT vs Tg+DOX, WT vs tTA, ¥Tg vs Tg+DOX, ¢Tg vs tTA and ¤Tg+DOX vs tTA

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