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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Longitudinal changes in EEG power, sleep cycles and behaviour in a tau model of neurodegeneration

Fig. 3

Sleep architecture changes over time in rTg4510 mice. Least squares means from 1-week recording periods every 4 weeks in the dark and light periods for wakefulness (a, b), NREM sleep (c, d) and REM sleep (e, f), respectively. Asterisks (*) denote statistical significance (p < 0.05) at the time point between WT vs Tg, WT vs Tg+DOX, WT vs tTA, ¥Tg vs Tg+DOX, ¢Tg vs tTA and ¤Tg+DOX vs tTA. Any statistical significance in groups compared with time is described in the text and not shown in the graphs (n = 12–23; p ≤ 0.05)

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