Quantitative EEG as a biomarker in mild cognitive impairment with Lewy bodies

Table 3 Results from receiver operating characteristic (ROC) analysis to distinguish MCI-AD from MCI-LB

EEG measure	AUC [95% CI]	Cutoff for MCI-LB	Sensitivity	Specificity
Delta power	0.54 [0.41, 0.67]	> 21.9	0.23	0.89
Theta power	0.60 [0.47, 0.73]	> 10.7	0.33	0.89
Pre-alpha power	0.68 [0.56, 0.81]	> 28.1	0.56	0.83
Alpha power	0.66 [0.53, 0.78]	< 20.5	0.41	0.97
Beta power	0.71 [0.59, 0.83]	< 19.0	0.61	0.81
Theta/alpha ratio	0.64 [0.51, 0.77]	> 0.56	0.49	0.83
DF, all electrodes	0.70 [0.58, 0.82]	< 7.1	0.51	0.86
DF, occipital electrodes	0.69 [0.57, 0.81]	< 7.1	0.51	0.86

The sensitivity/specificity cutoff was determined using Youden’s index
AUC area under the receiver operating curve, CI confidence interval, DF dominant frequency, MCI-AD mild cognitive impairment with Alzheimer’s disease, MCI-LB probable mild cognitive impairment with Lewy bodies

ISSN: 1758-9193