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Table 2 Group comparison of quantitative EEG characteristics

From: Quantitative EEG as a biomarker in mild cognitive impairment with Lewy bodies

  HC MCI-AD MCI-LB Group comparison
Delta power 14.1 [11.3, 17.0] 14.1 [11.8, 16.3] 14.9 [12.7, 17.1] F(2, 102) = 0.8, p = 0.47
Theta power 5.7 [4.6, 6.9] 7.0 [6.0, 8.1] 8.8 [7.2, 10.3] F(2, 102) = 4.8, p = 0.01
p(HC,MCI-AD) = 0.19
p(HC,MCI-LB) = 0.004
p(MCI-AD,MCI-LB) = 0.46
Pre-alpha power 13.3 [9.9, 16.7] 19.6 [16.1, 23.1] 28.8 [24.2, 33.4] F(2, 102) = 16.0, p < 0.001
p(HC,MCI-AD) = 0.006
p(HC,MCI-LB) < 0.001
p(MCI-AD,MCI-LB) = 0.02
Alpha power 39.9 [34.1, 45.6] 33.6 [29.3, 37.9] 28.3 [23.6, 33.1] F(2, 102) = 5.5, p = 0.005
p(HC,MCI-AD) = 0.39
p(HC,MCI-LB) = 0.001
p(MCI-AD,MCI-LB) = 0.07
Beta power 26.7 [22.9, 30.4] 25.4 [22.4, 28.4] 18.9 [15.3, 22.5] F(2, 102) = 8.1, p = 0.001
p(HC,MCI-AD) = 1.0
p(HC,MCI-LB) < 0.001
p(MCI-AD,MCI-LB) = 0.001
Theta/alpha ratio 0.34 [0.27, 0.40] 0.42 [0.36, 0.47] 0.51 [0.44, 0.57] F(2, 102) = 7.5, p < 0.001
p(HC,MCI-AD) = 0.22
p(HC,MCI-LB) = 0.001
p(MCI-AD,MCI-LB) = 0.10
DF, all electrodes 8.4 [8.0, 8.9] 8.0 [7.6, 8.3] 7.2 [6.8, 7.6] F(2, 102) = 8.7, p < 0.001
p(HC,MCI-AD) = 0.29
p(HC,MCI-LB) < 0.001
p(MCI-AD,MCI-LB) = 0.01
DF, occipital electrodes 8.5 [8.1, 9.0] 8.0 [7.6, 8.3] 7.3 [6.9, 7.7] F(2, 102) = 8.7, p < 0.001
p(HC,MCI-AD) = 0.16
p(HC,MCI-LB) < 0.001
p(MCI-AD,MCI-LB) = 0.03
DFV, occipital electrodes 1.3 [0.9, 1.6] 1.4 [1.1, 1.7] 1.0 [0.8, 1.2] F(2, 102) = 3.6, p = 0.03
p(HC,MCI-AD) = 0.54
p(HC,MCI-LB) = 1.0
p(MCI-AD,MCI-LB) = 0.17
  1. Mean [95% confidence interval] of different quantitative EEG characteristics. Group comparisons were performed using univariate ANOVAs followed by post hoc tests, Bonferroni-corrected for multiple comparisons. Sex was included as a covariate
  2. DF dominant frequency, DFV dominant frequency variability, HC healthy controls, MCI-AD mild cognitive impairment with Alzheimer’s disease, MCI-LB probable mild cognitive impairment with Lewy bodies