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Table 2 Group comparison of quantitative EEG characteristics

From: Quantitative EEG as a biomarker in mild cognitive impairment with Lewy bodies

 

HC

MCI-AD

MCI-LB

Group comparison

Delta power

14.1 [11.3, 17.0]

14.1 [11.8, 16.3]

14.9 [12.7, 17.1]

F(2, 102) = 0.8, p = 0.47

Theta power

5.7 [4.6, 6.9]

7.0 [6.0, 8.1]

8.8 [7.2, 10.3]

F(2, 102) = 4.8, p = 0.01

p(HC,MCI-AD) = 0.19

p(HC,MCI-LB) = 0.004

p(MCI-AD,MCI-LB) = 0.46

Pre-alpha power

13.3 [9.9, 16.7]

19.6 [16.1, 23.1]

28.8 [24.2, 33.4]

F(2, 102) = 16.0, p < 0.001

p(HC,MCI-AD) = 0.006

p(HC,MCI-LB) < 0.001

p(MCI-AD,MCI-LB) = 0.02

Alpha power

39.9 [34.1, 45.6]

33.6 [29.3, 37.9]

28.3 [23.6, 33.1]

F(2, 102) = 5.5, p = 0.005

p(HC,MCI-AD) = 0.39

p(HC,MCI-LB) = 0.001

p(MCI-AD,MCI-LB) = 0.07

Beta power

26.7 [22.9, 30.4]

25.4 [22.4, 28.4]

18.9 [15.3, 22.5]

F(2, 102) = 8.1, p = 0.001

p(HC,MCI-AD) = 1.0

p(HC,MCI-LB) < 0.001

p(MCI-AD,MCI-LB) = 0.001

Theta/alpha ratio

0.34 [0.27, 0.40]

0.42 [0.36, 0.47]

0.51 [0.44, 0.57]

F(2, 102) = 7.5, p < 0.001

p(HC,MCI-AD) = 0.22

p(HC,MCI-LB) = 0.001

p(MCI-AD,MCI-LB) = 0.10

DF, all electrodes

8.4 [8.0, 8.9]

8.0 [7.6, 8.3]

7.2 [6.8, 7.6]

F(2, 102) = 8.7, p < 0.001

p(HC,MCI-AD) = 0.29

p(HC,MCI-LB) < 0.001

p(MCI-AD,MCI-LB) = 0.01

DF, occipital electrodes

8.5 [8.1, 9.0]

8.0 [7.6, 8.3]

7.3 [6.9, 7.7]

F(2, 102) = 8.7, p < 0.001

p(HC,MCI-AD) = 0.16

p(HC,MCI-LB) < 0.001

p(MCI-AD,MCI-LB) = 0.03

DFV, occipital electrodes

1.3 [0.9, 1.6]

1.4 [1.1, 1.7]

1.0 [0.8, 1.2]

F(2, 102) = 3.6, p = 0.03

p(HC,MCI-AD) = 0.54

p(HC,MCI-LB) = 1.0

p(MCI-AD,MCI-LB) = 0.17

  1. Mean [95% confidence interval] of different quantitative EEG characteristics. Group comparisons were performed using univariate ANOVAs followed by post hoc tests, Bonferroni-corrected for multiple comparisons. Sex was included as a covariate
  2. DF dominant frequency, DFV dominant frequency variability, HC healthy controls, MCI-AD mild cognitive impairment with Alzheimer’s disease, MCI-LB probable mild cognitive impairment with Lewy bodies