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Table 1 Demographic and clinical variables, mean (standard deviation)

From: Quantitative EEG as a biomarker in mild cognitive impairment with Lewy bodies

 

HC (N = 31)

MCI-AD (N = 36)

MCI-LB (N = 39)

Group differences

Male to female

22:9

15:21

35:4

χ2 = 20.0, p < 0.001a

p(HC,MCI-AD) = 0.02

p(HC,MCI-LB) = 0.045

p(MCI-AD,MCI-LB) < 0.001

Age

73.7 (7.3)

76.1 (7.7)

74.7 (6.4)

F(2, 103) = 1.0, p = 0.38b

AChEI

7 (19%)e

18 (46%)f

χ2 = 5.7, p = 0.02c

PD meds

0e

4 (10%)f

χ2 = 3.8, p = 0.052c

Years of education

14.7 (4.0)g

12.9 (3.4)h

12.1 (2.8)

F(2, 100) = 5.1, p = 0.008c

p(HC,MCI-AD) = 0.12

p(HC,MCI-LB) = 0.006

p(MCI-AD,MCI-LB) = 0.87

ACE-R

92.7 (4.2)

82.4 (8.5)

83.8 (9.2)

t73 = 0.7, p = 0.50d

MMSE

28.5 (1.1)

26.9 (2.1)

26.6 (2.5)

t73 = 0.7, p = 0.51d

UPDRS III

5.5 (4.4)

15.1 (13.8)

23.3 (14.2)

t73 = 2.5, p = 0.01d

DCFS

6.9 (1.9)i

8.5 (3.3)k

t61 = 2.4, p = 0.02d

CAF total

1.4 (2.7)i

3.7 (4.2)k

t61 = 2.5, p = 0.02d

NPI total

8.6 (9.3)i

16.4 (12.9)k

t61 = 2.7, p = 0.01d

NEVHI

0.8 (1.5)e

2.7 (4.1)

t71 = 2.6, p = 0.01d

GDS

1.3 (1.8)

3.5 (2.5)

5.1 (4.1)

F(2, 103) = 13.4, p < 0.001b

p(HC,MCI-AD) = 0.01

p(HC,MCI-LB) < 0.001

p(MCI-AD,MCI-LB) = 0.08

  1. ACE-R Addenbrooke’s Cognitive Examination–Revised, AChEI number of patients taking acetylcholinesterase inhibitors, CAF total clinician assessment of fluctuation total score, DCFS Dementia Cognitive Fluctuation Scale, GDS Geriatric Depression Scale, HC healthy controls, MCI-AD mild cognitive impairment with Alzheimer’s disease, MCI-LB probable mild cognitive impairment with Lewy bodies, MMSE Mini-Mental State Examination, NEVHI North-East Visual Hallucinations Interview, NPI Neuropsychiatric Inventory, PD meds number of patients taking dopaminergic medication for the management of Parkinson’s disease symptoms, UPDRS III Unified Parkinson’s Disease Rating Scale III (motor subsection)
  2. aChi-square test HC, MCI-AD, MCI-LB
  3. bUnivariate ANOVA HC, MCI-AD, MCI-LB
  4. cChi-square test MCI-AD, MCI-LB
  5. dStudent’s t test MCI-AD, MCI-LB
  6. eN = 34
  7. fN = 38
  8. gN = 29
  9. hN = 35
  10. iN = 27
  11. kN = 36