Fig. 1

MRI (top), FDG PET (middle), and tau PET (bottom) comparisons between the AD groups and CN. The significance maps show p < 0.05 thresholded FWE cluster-level corrected results of EOADMCI (N = 60), EOADDEM (N = 50), LOADMCI (N = 216), and LOADDEM (N = 148) vs. CN (N = 291). The results displayed here are for all subjects with available scans in each modality