From: Diverse proteins aggregate in mild cognitive impairment and Alzheimer’s disease brain
Protein name | Ratio AD/control | Adjusted P value rank t test | Adjusted P value, log/quant t test | Description |
---|---|---|---|---|
CAMK2G | 34.1 | 0.35284 | 0.36965 | Calcium/calmodulin-dependent protein kinase type II subunit gamma |
VARS | 7.5 | 0.02652 | 0.02652 | Valine-tRNA ligase |
CORO1A | 6.4 | 0.00292 | 0.01072 | Coronin |
UBC | 6.1 | 0.18882 | 0.16372 | Polyubiquitin-C |
APOE | 6 | 0.24853 | 0.25648 | Apolipoprotein E |
CADPS | 5.9 | 0.02406 | 0.02181 | Calcium-dependent secretion activator 1 |
UBB | 5.9 | 0.18882 | 0.16481 | Ubiquitin |
UBA52 | 5.8 | 0.07478 | 0.05029 | Ubiquitin-60S ribosomal protein L40 |
FN1 | 5.5 | 0.27685 | 0.26619 | Fibronectin |
CRMP1 | 5.4 | 0.15919 | 0.15661 | Dihydropyrimidinase-related protein 1 |
GPI | 5.3 | 0.04530 | 0.02897 | Glucose-6-phosphate isomerase |
USP14 | 5.2 | 0.05072 | 0.05530 | Ubiquitin carboxyl-terminal hydrolase 14 |
DNM1L | 5.1 | 0.04185 | 0.06481 | Dynamin-1 |
DBNL | 5.1 | 0.18936 | 0.22434 | Drebrin |
TOMM70A | 5 | 0.12050 | 0.11536 | Mitochondrial import receptor subunit TOM70 |
UBA1 | 4.9 | 0.06626 | 0.08523 | Ubiquitin-like modifier-activating enzyme 1 |
SND1 | 4.6 | 0.02578 | 0.03000 | Staphylococcal nuclease domain-containing protein 1 |
NNT | 4.6 | 0.03093 | 0.02652 | NAD(P) transhydrogenase, mitochondrial |
XRCC6 | 4.3 | 0.04042 | 0.05530 | KU-70 |
DLAT | 4.2 | 0.02720 | 0.02652 | Acetyltransferase component of pyruvate dehydrogenase complex |
ACOT7 | 4.1 | 0.15434 | 0.16372 | Cytosolic acyl coenzyme A thioester hydrolase |
PPP2R4 | 4.1 | 0.02578 | 0.02652 | Serine/threonine-protein phosphatase 2A activator |
PLXNA1 | 4.0 | 0.08108 | 0.10703 | Plexin-A1 |
PGRMC1 | 3.9 | 0.02447 | 0.01072 | Membrane-associated progesterone receptor component 1 |
VPS35 | 3.8 | 0.04996 | 0.04909 | Vacuolar protein sorting-associated protein 35 |
ATP2A2 | 3.8 | 0.04735 | 0.03000 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 |
KIF2C | 3.6 | 0.02777 | 0.03000 | Kinesin |
MAPK3 | 3.6 | 0.02082 | 0.02652 | Mitogen-activated protein kinase 3 |
HSPA12B | 3.5 | 0.53236 | 0.52338 | Heat shock 70 kDa protein 12B |
RTN4 | 3.2 | 0.04345 | 0.07768 | Reticulon-4 |
ARHGDIA | 3.2 | 0.08045 | 0.09469 | Rho GDP-dissociation inhibitor 1 |
FASN | 3 | 0.08108 | 0.02652 | Fatty acid synthase |
XRCC5 | 2.9 | 0.05787 | 0.11224 | KU-80 |
UCHL1 | 2 | 0.08705 | 0.03192 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 |