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Table 4 MSDRs for step-by-step iterations from the − 10 to 0 composite applied to different intervals

From: The Alzheimer’s Prevention Initiative Composite Cognitive Test: a practical measure for tracking cognitive decline in preclinical Alzheimer’s disease

Composite− 10 to 0− 11 to − 1− 5 to − 1
Combination 1:
 Symbol Digit Modalities
 Digit Ordering
 MMSE Orientation to Time
 Logical Memory Delayed
 Word List Memory Delayed
 Judgment of Line Orientation
 Raven’s Progressive Matrices (subset of 9 items from A and B)
− 1.06− 0.5331− 0.4047
Combination 2:
 Symbol Digit Modalities
 Digit Ordering
 MMSE Orientation to Time
 MMSE Orientation to Place
 Logical Memory Delayed
 Word List Memory Delayed
 Judgment of Line Orientation
 Raven’s Progressive Matrices (subset of 9 items from A and B)
−1.09− 0.5460− 0.4172
Combination 3 (APCC):
 Symbol Digit Modalities
 MMSE Orientation to Time
 MMSE Orientation to Place
 Logical Memory Delayed
 Word List Memory Delayed
 Judgment of Line Orientation
 Raven’s Progressive Matrices (subset of 9 items from A and B)
− 1.10− 0.5386− 0.4124
  1. MMSE Mini-Mental State Examination, MSDR mean-to-standard deviation ratio