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Table 3 Pearson correlation coefficients (r) between functional connectivity (FC) and disease severity represented by MMSE. Correlations were estimated for the entire population (cohorts 1 and 2) and the AD subjects only. Bold r values indicate a significant (p < 0.05) correlation

From: Reproducibility of EEG functional connectivity in Alzheimer’s disease

FC measure versus MMSE

All subjects (n = 809)

AD only (n = 410)

r

p-value

r

p-value

Theta (4–8 Hz)

 iCoh

− 0.13

1.41 × 10−4

− 0.06

0.23

 PLI

− 0.13

2.79 × 10−4

− 0.06

0.23

 wPLI

− 0.13

1.71 × 10−4

− 0.06

0.21

Alpha (8–13 Hz)

 AEC-c

0.21

3.2 × 10−9

0.14

0.0054

 AEC

0.35

6.1 × 10−25

0.14

0.0065

 Coh

0.27

6.4 × 10−15

0.04

0.40

 PLV

0.23

7.3 × 10−11

0.08

0.13

Beta (13–30 Hz)

 AEC-c

0.21

1.8 × 10−9

0.08

0.12

 AEC

0.26

1.0 × 10−13

0.13

0.0073

 Coh

0.22

3.1 × 10−10

0.12

0.015