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Table 1 Baseline demographic characteristics of patients enrolled in the ALZ2002 (safety set)

From: Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer’s disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension study

Baseline characteristics

Treatment group at start ALZ2002

Placebo

10 mg

50 mg

Total

N

39

37

38

114

Sex, men,n(%)

16 (41.0)

18 (48.6)

20 (52.6)

54 (47.4)

Age, years

    

Mean (SD)

70.3 (5.38)

70.9 (6.58)

68.1 (8.55)

69.8 (6.99)

Range

59; 80

52; 81

50; 82

50; 82

Race

    

White,n(%)

37 (94.9)

36 (97.3%)

38 (100.0)

111 (97.4)

Other,n(%)

2 (5.1)

1 (2.7)

0 (0.0)

3 (2.6)

APOEε4 carrier status known,n

27

30

22

79

Yes,n(%)

17 (63.0)

18 (60.0)

10 (45.5)

45 (57.0)

No,n(%)

10 (37.0)

12 (40.0)

11 (50.0)

33 (41.8)

Preclinical AD, CDR = 0,n(%)

7 (17.9)

8 (21.6)

9 (23.7)

24 (21.1)

MCI due to AD, CDR = 0.5,n(%)

32 (82.1)

29 (78.4)

29 (76.3)

90 (78.9)