Fig. 4From: Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer’s disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension studya Box-whisker plots of percent change from baseline for CSF sAPPα and sAPPβ biomarkers by final dose groups at month 6 of atabecestat treatment in ALZ2002 and b for percent change from ALZ2002 baseline for CSF sAPPα and sAPPβ to week 52 in the ALZ2004 double-blind periodBack to article page