Table 2 Number of significant S-PrediXcan associations per tissue
Tissue | Tissue sample size (N) | Gene associations (N) | Genes |
|---|---|---|---|
Skin, sun-exposed lower leg | 414 | 10 | APOE, APOC1, NECTIN2, SIX5, CLU, CLPTM1, ZNF229, ZYX, PPP1R13L, KLC3 |
Lung | 383 | 8 | RELB, APOE, CEACAM19, APOC2, APOC1, APOC4, MS4A2, DMPK |
Oesophagus mucosa | 358 | 8 | PPP1R13L, KLC3, EPHA1, ZNF234, MS4A2, RP11-385F7.1, TOMM40, PVR |
Oesophagus muscularis | 335 | 6 | NECTIN2, BLOC1S3, CR1, CEACAM19, BIN1, PVR |
Skin, not sun-exposed suprapubic | 335 | 6 | APOE, APOC2, ZNF229, CLPTM1, MS4A2, PVR |
Adrenal gland | 175 | 4 | APOC1, APOC4, QPCTL, CEACAM19 |
Brain hippocampus | 111 | 4 | CEACAM19, CR1, NECTIN2, HLA-DQA2 |
Pancreas | 220 | 4 | CEACAM19, CBLC, FOSB, BCAM |
Spleen | 146 | 4 | PVR, FZD4, CEACAM19, SIX5 |
Stomach | 237 | 4 | MS4A2, ZNF45, CBLC, CEACAM19 |