Sex-specific associations with cerebrospinal fluid biomarkers in dementia with Lewy bodies

Table 2 Cerebrospinal fluid concentrations at baseline

	Women, n = 39	Men, n = 184	Model 1^a		Model 2^b
	Women, n = 39	Men, n = 184	Adjusted mean difference β coefficient (95%CI)	p value	Adjusted mean difference β coefficient (95%CI)	p value
α-syn^c	1558 ± 431	1895 ± 707	− 390 (− 731:− 48)	0.03	− 309 (− 657:− 40)	0.08
Aβ42	696 ± 210	824 ± 251	− 108 (− 190:− 26)	0.01	−103 (− 191:− 14)	0.02
Tau^d	5.9 ± 0.6	5.7 ± 0.5	0.10 (− 0.09:− 0.29)	0.31	0.06 (− 0.14:− 0.03)	0.55
pTau^d	3.9 ± 0.5	3.9 ± 0.5	0.03 (− 0.13:0.19)	0.74	0.01 (−0.15:0.17)	0.90

Data presented as mean ± SD
^aModel 1: adjusted for age
^bModel 2: adjusted for age and APOEe4 genotype
^cα-syn results were available for n = 117 (f = 17; m = 100)
^dAnalyses were performed with LN transformed data to meet assumptions of normality

ISSN: 1758-9193