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Table 1 Baseline characteristics

From: Sex-specific associations with cerebrospinal fluid biomarkers in dementia with Lewy bodies

 Women, n = 39Men, n = 184p value
Age70.1 ± 6.067.7 ± 7.30.04
Education, years11.0 ± 2.811.4 ± 2.90.42
Duration of complaints, years2.3 ± 1.23.5 ± 2.8< 0.001
APOE ɛ4 carrier,n(%)22 (70%)86 (52%)0.08
Geriatric Depression Scale (0–15)4 ± 34 ± 30.65
Core clinical features,n(%)
 Visual hallucinations, n = 22223 (59%)69 (38%)0.02
 Parkinsonism, n = 21623 (62%)130 (73%)0.28
 RBD, n = 15611 (55%)99 (73%)0.17
 Cognitive fluctuations, n = 17329 (94%)119 (84%)0.26
Cognitive test scoresa,n = 205
 MMSE21 ± 623 ± 40.02
 RAVLT—immediate recall− 1.94 ± 1.10− 2.00 ± 0.950.74
 RAVLT—delayed recall− 1.80 ± 0.98− 1.72 ± 0.960.84
 VAT—12 items− 6.20 ± 5.78− 4.87 ± 4.990.31
 TMT-Ab− 5.47 ± 6.46− 4.60 ± 4.840.52
 TMT-B/Ab,c− 6.93 ± 7.03− 5.33 ± 6.420.32
 Animal fluency− 2.38 ± 1.02− 1.78 ± 0.990.002
Biomarker status, abnormal/available,n(%)
 DAT SPECT, n = 10715/15 (100%)79/91 (87%)0.06
 CSF Aβ42 status30/39 (77%)104/186 (56%)0.02
 Abnormal Tau/Aβ42 ratio (> 0.52)21/38 (55%)55/185 (30%)0.002
  1. Data represent mean ± SD, median [IQR] or n (%). Parkinsonism: bradykinesia, rigidity, or tremor
  2. MMSE Mini Mental State Examination, RAVLT Raven auditory verbal learning test (Dutch version), VAT Visual Association Test, TMT Trail Making Test
  3. aAdjusted for age and education. Data of RAVLT, VAT, TMT, and animal fluency represent z scores, based on cognitively healthy subjects
  4. bData are inverted and log-transformed
  5. cMissing values are imputed based on TMT-B/A ratio for n = 101