Table 1 Characteristics of cases and controls (with and without dementia) with rheumatoid arthritis used in this study
Case (with dementia diagnosis) | Control (no dementia diagnosis) | p value | |
|---|---|---|---|
n | 486 | 641 | – |
Age at index date (years) | 79.8 (± 6.89) | 79.5 (± 7.02) | 0.522 |
Gender | 86.4% F | 87.4% F | 0.707 |
Time since rheumatoid arthritis diagnosis before the index date (years) | 6.87 (± 6.29) | 7.06 (± 5.92) | 0.232 |
Prescribed with sulfasalazine | 40 (8.23%) | 57 (8.89%) | 0.776 |
Years of sulfasalazine use before the index date | 2.72 (± 3.57) | 2.57 (± 3.96) | 0.457 |
Prescribed with methotrexate | 123 (25.3%) | 178 (27.77%) | 0.392 |
Years of methotrexate use before the index date | 2.69 (± 3.06) | 3.80 (± 2.44) | 0.002 |
Prescribed with methotrexate or sulfasalazine | 19 (3.91%) | 25 (3.90%) | 1.000 |
Diagnosed with AMI | 26 (5.35%) | 34 (5.30%) | 1.000 |
Diagnosed with stroke | 37 (7.60%) | 64 (10.00%) | 0.202 |
Highest BMI before the index date | 28.1 (± 4.99) | 28.8 (± 4.90) | 0.061 |
BMI missingness | 178 (36.62%) | 211 (32.92%) | 0.217 |
Total time in database (years) | 7.64 (± 7.82) | 7.77 (± 7.66) | 0.301 |
Time in database before the index date (years) | 5.16 (± 7.47) | 4.62 (± 7.01) | 0.027 |