Fig. 3

Site occupancy of phosphorylation on T181 and T217 in the two cohorts. The percentage of T181 and T217 phosphorylation corresponding to the amount of the phosphorylated peptide divided by the sum of the phosphorylated and non-phosphorylated peptide was plotted in the two cohorts. Significant differences between NAD and AD or amyloid (−) and (+) populations for the two peptides were observed (see also Sup Table 2)