Fig. 1
From: Elecsys CSF biomarker immunoassays demonstrate concordance with amyloid-PET imaging
Box and whisker plots of CSF biomarkers by Aβ-PET status and clinical classification. a Aβ42, b Aβ42/Aβ40 ratio, c tTau, d tTau/Aβ42 ratio, e pTau and f pTau/Aβ42 ratio. Dashed lines represent threshold values for each CSF biomarker as calculated via ROC analyses. Abbreviations: Aβ, β-amyloid; Aβ42, β-amyloid (1–42); Aβ42/Aβ40, β-amyloid (1–42)/β-amyloid (1–40) ratio; AD, Alzheimer’s disease; CSF, cerebrospinal fluid; HC, healthy controls; MCI, mild cognitive impairment; PET, positron emission tomography; pTau, phosphorylated tau (181P); pTau/Aβ42, phosphorylated tau (181P)/β-amyloid (1–42) ratio; ROC, receiver operating characteristic; tTau, total tau; tTau/Aβ42, total tau/β-amyloid (1–42) ratio