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Table 4 Cognitive test cutoffs at 1.5 SD from mean for cohorts A, B and E

From: The age-related effect on cognitive performance in cognitively healthy elderly is mainly caused by underlying AD pathology or cerebrovascular lesions: implications for cutoffs regarding cognitive impairment

 Cohort A cutoffs (95% CI)Cohort B cutoffs (95% CI)Cohort E cutoffs (95% CI)
ADAS-delayed recall4.88 (4.59–5.16)4.38 (4.13–4.61)3.93 (3.63–4.20)
ADAS naming1.57 (1.42–1.71)1.44 (1.29–1.58)1.25 (1.01–1.48)
Animal Fluency13.5 (13.1–13.9)14.0 (13.6–14.4)15.0 (14.4–15.7)
AQT85.3 (83.6–86.9)83.5 (81.8–85.2)80.0 (77.8–82.1)
Stroop40.0 (39.0–40.9)39.0 (38.0–39.8)36.9 (35.1–38.6)
TMT A71.5 (69.2–73.9)71.3 (68.9–73.8)59.0 (56.5–61.2)
TMT B180.6 (172.1–189.0)176.0 (167.8–184.4)144.6 (135.5–152.5)
SDMT24.3 (23.7–25.0)25.1 (24.4–25.8)27.2 (26.1–28.3)
  1. Cutoffs (1.5 SD from mean) created from 500 bootstrap samples. We found significantly improved cutoffs in cohort E compared to cohort A for all tests apart from ADAS naming. We found significantly improved cutoffs in cohort E compared to the traditional method of creating robust norms (cohort B) for Animal Fluency, TMT A, TMT B, and SDMT, i.e., non-overlapping 95% CIs (presented in bold)