Fig. 1

ROC curves: corrected Centiloids and neuropathologic results. Receiver Operator Characteristic curve for corrected Centiloid (CL) units thresholds in determining a) “low” vs “high” C score neuritic amyloid plaque burden (optimal threshold 21.3 CL, Youden J= 0.893) ; b) “none” vs “any” C score neuritic amyloid plaque burden (optimal threshold 9.6 CL, Youden J= 0.875); and c) “unlikely Alzheimer’s disease” (not/low scores) vs “likely Alzheimer’s Disease” (intermediate/high scores) using Alzheimer’s Disease Neuropathologic Change evaluation (optimal threshold 49.4 CL, Youden J= 0.863)