Table 2 Demographics for the sub-cohort dichotomized into β-amyloid positive (Aβ+) and β-amyloid negative (Aβ−) groups
Characteristics | Aβ+ (n = 676) | Aβ− (n = 755) | |
|---|---|---|---|
Gender, n (%) | Male | 300 (44%) | 338 (45%) |
Female | 376 (56%) | 417 (55%) | |
Clinical diagnosis, n (%) | AD | 202 (30%) | 26 (3%) |
MCI | 192 (28%) | 117 (16%) | |
SCD | 84 (13%) | 133 (18%) | |
Controls | 198 (29%) | 479 (63%) | |
Age, median (IQR) | 73 (8) | 71 (8) | |
AD biomarkers, median (IQR) | |||
 MMSE | 27 (5) | 29 (2) | |
 Aβ40, pg/mL | 5851 (2776) | 5423 (2474) | |
 Aβ42, pg/mL | 338.8 (184.0) | 697.6 (330.4) | |
 Aβ42/40 | 0.059 (0.024) | 0.130 (0.029) | |
 t-tau, pg/mL | 496.2 (268.1) | 276.5 (110.0) | |
 p-tau, pg/mL | 88.16 (64.70) | 34.48 (14.56) | |
ApoE, median (IQR) | |||
 Total apoE, μg/mL | 3.112 (1.491) | 3.012 (1.465) | |