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Table 3 Brain regions negatively correlated with the time on the Trail Making Test A (TMTA; significant at p < .05, FDR corrected) and positively correlated with raw scores on the Digit Symbol Substitution Test (DSST; significant at p < .001 uncorrected) for the DLB group

From: Pay attention to the basal ganglia: a volumetric study in early dementia with Lewy bodies

Brain region

R/L

BA

k

x

y

z

T

TMTA (N = 87)

 Cluster 1

  Caudate nucleus (head and body)

L

na

1033/1646

− 15

10.5

9

5.07*

  Putamen

L

na

121/1646

− 18

15

3

3.71

  Globus pallidus

L

na

18/1646

− 13.5

4.5

3

3.6

  Thalamus (ventral anterior nucleus)

L

na

21/1646

− 10

− 1.5

6

3.2

 Cluster 2

  Caudate nucleus (head and body)

R

na

1000/1484

12

0

13.5

4.44

  Putamen

R

na

114/1484

22.5

13.5

10.5

3.82

 Cluster 3

  Subthalamic nucleus

L/R

na

230

− 4.5

− 13.5

− 3

4.1

DSST (N = 81)

 Cerebellum

L

na

268

− 43.5

− 70.5

− 43.5

4.1

 Thalamus (ventral lateral nucleus)

L

na

201

− 15

− 16.5

10.5

3.77

 Inferior frontal gyrus

R

44/45

105

55.5

18

19.5

3.59

  1. x, y, z MNI coordinates of the cluster peak; BA Brodmann area; k cluster extent; T t value for the cluster peak
  2. *Cluster peak significant at p < .05 FWE corrected